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Takuro Numaga-Tomita Selected Research

TRPC3 cation channel

1/2017TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice.
12/2016TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.

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Takuro Numaga-Tomita Research Topics

Disease

7Heart Failure
01/2022 - 01/2014
4Cardiovascular Diseases (Cardiovascular Disease)
01/2019 - 01/2014
3Atrophy
01/2019 - 08/2017
3Hypertension (High Blood Pressure)
12/2017 - 01/2016
3Fibrosis (Cirrhosis)
01/2017 - 12/2016
2Cardiotoxicity
01/2019 - 08/2017
2Hypertrophy
01/2018 - 01/2016
1Malnutrition (Nutritional Deficiencies)
01/2019
1Weight Loss (Weight Reduction)
01/2019
1Hypoxia (Hypoxemia)
11/2018
1Infarction (Infarctions)
11/2018
1Cardiomegaly (Heart Hypertrophy)
01/2018
1Left Ventricular Dysfunction
08/2017
1Cardiomyopathies (Cardiomyopathy)
08/2017
1Vascular Remodeling
06/2017
1Hyperglycemia
01/2017
1Inflammation (Inflammations)
01/2016
1Myocardial Infarction
01/2014

Drug/Important Bio-Agent (IBA)

4GTP-Binding Proteins (G-Protein)IBA
01/2022 - 01/2016
3Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2014
2ArrestinIBA
11/2020 - 01/2016
2Pharmaceutical PreparationsIBA
11/2020 - 06/2017
2Adenosine Triphosphate (ATP)IBA
01/2019 - 01/2018
2FilaminsIBA
01/2019 - 11/2018
2Antineoplastic Agents (Antineoplastics)IBA
01/2019 - 08/2017
2Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019 - 08/2017
2NADPH Oxidase 2IBA
01/2019 - 01/2017
2Angiotensin IIIBA
01/2018 - 01/2016
2NucleotidesIBA
01/2018 - 12/2017
2N,N''- 1,4- butanediylbis(N'- (3- isothiocyanatophenyl))thioureaIBA
12/2017 - 01/2016
2AngiotensinsIBA
12/2017 - 01/2016
2purinoceptor P2Y6IBA
06/2017 - 01/2016
2TRPC3 cation channelIBA
01/2017 - 12/2016
1Sar-Arg-Val-Tyr-Ile-His-Pro-Ala-OHIBA
11/2020
1Dihydrotachysterol (AT 10)IBA
01/2019
1Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA
01/2019
1Environmental Pollutants (Pollutants, Environmental)IBA
01/2019
1Purinergic P2Y2 ReceptorsIBA
01/2019
1cilnidipineIBA
11/2018
1Purinergic Receptors (Receptors, Purine)IBA
01/2018
1Adenosine (Adenocard)FDA LinkGeneric
01/2018
1LigandsIBA
01/2018
1Endothelin-1 (Endothelin 1)IBA
01/2018
1Purinergic P2Y ReceptorsIBA
12/2017
1UridineIBA
12/2017
1Type 1 Angiotensin ReceptorIBA
06/2017
1Uridine Diphosphate (UDP)IBA
06/2017
1Clopidogrel (Plavix)FDA Link
06/2017
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2017
1TRPC6 Cation ChannelIBA
01/2017
1Extracellular Matrix ProteinsIBA
01/2017
1rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA
12/2016
1Guanine NucleotidesIBA
01/2016
1Carrier Proteins (Binding Protein)IBA
01/2016
1Heterotrimeric GTP-Binding Proteins (Heterotrimeric G-Proteins)IBA
01/2016
1Cysteine (L-Cysteine)FDA Link
01/2014
1Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2014
1Sulfhydryl Compounds (Thiols)IBA
01/2014
1Nitric Oxide Synthase (NO Synthase)IBA
01/2014
1SulfurIBA
01/2014
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2014